Diagnostic approach to interstitial lung disease

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Interstitial lung disease - An approach to diagnosis and management.

BACKGROUND Interstitial lung disease (ILD) is a term that describes a diverse range of lung conditions, which are an important cause of morbidity and mortality in all age groups. Idiopathic pulmonary fibrosis is the most common ILD in older adults and generally has a poor prognosis. Sarcoidosis is more common in younger adults and generally has a more benign prognosis. OBJECTIVE This article ...

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Approach to the diagnosis of interstitial lung disease.

Interstitial lung diseases (ILDs) encompass a wide range of diffuse pulmonary disorders, characterized by a variable degree of inflammatory and fibrotic changes of the alveolar wall and eventually the distal bronchiolar airspaces. ILDs may occur in isolation or in association with systemic diseases. The clinical evaluation of a patient with ILD includes a thorough medical history and detailed p...

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[Diagnostic value of induced sputum in interstitial lung disease].

BACKGROUND Induced sputum (IS) has been recently used to investigate pulmonary inflammation in patients with interstitial lung disease (ILD), but still little attention has been paid to its efficacy in diagnosing sarcoidosis and other ILD. The aim of this study was to evaluate the diagnostic value of IS differential cell count and CD4+/CD8+ ratio in sarcoidosis (SA) and nonsarcoidosis ILD (NSA ...

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Drug-induced interstitial lung disease: mechanisms and best diagnostic approaches

Drug-induced interstitial lung disease (DILD) is not uncommon and has many clinical patterns, ranging from benign infiltrates to life-threatening acute respiratory distress syndrome. There are two mechanisms involved in DILD, which are probably interdependent: one is direct, dose-dependent toxicity and the other is immune-mediated. Cytotoxic lung injury may result from direct injury to pneumocy...

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Rheumatoid Arthritis-Associated Interstitial Lung Disease: Diagnostic Dilemma

Interstitial lung disease (ILD) is an increasingly recognized complication of rheumatoid arthritis (RA) contributing to significantly increased morbidity and mortality. Diagnosis can be challenging since patients are unlikely to report dyspnea due to an overall decrease in physical activity with advanced arthritic symptoms. Additionally, infections, drug toxicity, and environmental toxins can m...

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ژورنال

عنوان ژورنال: Current Respiratory Care Reports

سال: 2012

ISSN: 2161-332X

DOI: 10.1007/s13665-012-0029-6